Get ready for a major walk down memory lane! It’s been over 20 years since Malcolm in the Middle first premiered on January 9, 2000 and, boy, do we feel old!

The fan-favorite series, which starred Bryan Cranston, Frankie Muniz, Christopher Masterson, Justin Berfield, Jane Kaczmarek and Erik Per Sullivan, with Hayden PanettiereCameron Monaghan and more pretty famous faces as guest stars over the years, followed a genius named Malcolm and showcased the daily antics of his extremely dysfunctional family. The show aired on FOX for seven seasons and 151 episodes until it came to its bittersweet end on May 14, 2006.

Since Malcolm in the Middle aired its final episode, some of its stars went on to have major acting careers while others completely stepped out of the Hollywood scene! What are they all up to now? Scroll through our gallery to find out what the cast has been doing for the past 14 years. 

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